Flow distribution uniformity in manifolds is important in various engineering applications.In this study, the effect Lip Makeup of manifold design on flow distribution is examined using both experimental and numerical methods.A comparison was made between a straight manifold and a gradually decreasing cross-sectional design considering two differen
AI Can Be a Powerful Social Innovation for Public Health if Community Engagement Is at the Core
There is a critical need for community engagement in the process of adopting artificial intelligence (AI) technologies in public health.Public health practitioners and researchers have historically innovated in areas like vaccination and sanitation but have been slower in adopting emerging technologies such as generative AI.However, with increasing
Therapeutic Antibody-Like Immunoconjugates against Tissue Factor with the Potential to Treat Angiogenesis-Dependent as Well as Macrophage-Associated Human Diseases
Accumulating evidence suggests that tissue factor (TF) is selectively expressed in pathological angiogenesis-dependent as well as macrophage-associated human diseases.Pathological angiogenesis, the formation of neovasculature, is involved in many clinically significant human diseases, notably cancer, age-related macular degeneration (AMD), endometr
Twelve tips for public health education using social media
With nearly half the world’s population using social media, platforms like Instagram, Twitter, and Facebook have become popular sources of information gathering and sharing for the general public.In medicine, social media is increasingly used Supplement to educate patients due its wide reach and interactive nature.Early studies showed that th
Integrative analysis of the lncRNA-miRNA-mRNA interactions in smooth muscle cell phenotypic transitions
Objectives: We previously found that the pluripotency factor OCT4 is reactivated in smooth muscle cells (SMC) in human and mouse atherosclerotic plaques and plays an atheroprotective role.Loss of OCT4 in SMC in vitro was associated with decreases in SMC migration.However, molecular mechanisms responsible for atheroprotective SMC-OCT4-dependent effe